Opening Ceremony takes many of the NYC's-coolest-store accolades, but in terms of edgy yet accessible, I actually prefer Oak. For one, it's much more affordable, particularly during its semiannual 30-40-50 sales (which last week hit 50% off, in case you were wondering). For another, it has all the cool designers you want—Alexander Wang, Cheap Monday, MM6—plus a bunch of new ones you haven't heard of yet, as well as a very cool in-house label. Even better, starting last Friday, Oak unveiled a secret sample sale in the basement of its Bond Street store, featuring true samples, accessories from photo shoots, and other treasures unearthed in storage. Shh, don't tell the hipsters. Ongoing; 28 Bond St. (Bowery & Lafayette Sts.), basement.
For those of you not in NYC, you can still shop the 30-40-50 sale online.